AND017
In normoxia, the enzyme called prolyl hydroxylase (PH) can hydroxylate hypoxiainducible-factor (HIF)
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| Program | Indication | Discovery | IND Approval | Phase I | Phase II | Phase III |
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AND017 (HIF-PHI) |
Non-Dialysis Dependent (NDD-CKD) Associated Anemia |
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AND017 (HIF-PHI) |
Dialysis Dependent Chronic Kidney Disease (DD-CKD) Associated Anemia |
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AND017 (HIF-PHI) |
Cancer Related Anemia (CRA) |
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AND017 (HIF-PHI) |
β-thalassemia |
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AND017 (HIF-PHI) |
Myelodysplastic Syndromes (MDS) Anemia |
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AND017 (HIF-PHI) |
Sickle Cell Disease (SCD) |
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AND019 (SERD) |
ER+/HER2-Breast Cancer |
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AND021 |
Renal Cell Carcinoma |
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ADC |
Cancers |
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